Clinical informatics deal with the decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.
Clinical informatics is tightly intricate with clinical guidelines
Modern Clinical guidelines known also as medical guidelines, clinical protocols or clinical practice guidelines are documents that identify, summarize and evaluate the highest quality evidence and most current data about prevention, diagnosis, prognosis, therapy including dosage of medications, risk/benefit and cost-effectiveness.
Then they define the most important questions related to clinical practice and identify all possible decision options and their outcomes.
Guidelines can use decision or computation algorithms integrating identified decision points and respective courses of action with clinical judgment and experience of practitioners.
Modern guidelines are based on scientific examination of current evidence based medicine.
The Guideline Interchange Format (GLIF) is a computer-interpretable language for modeling and executing clinical practice guidelines. GLIF supports sharing of computer-interpretable clinical guidelines across different medical institutions and system platforms
The first clinical guidelines date from Antiquity and where often based on traditional beliefs or religious authority (shamanism).